Norman G. Anderson

Biography

Norman G. Anderson, Ph.D. is Senior Scientific Advisor to the Plasma Proteome Institute, Washington DC (www.plasmaproteome.org). The Institute aims to foster a comprehensive exploration of the proteins of human blood plasma (the plasma proteome) and the rapid application of novel protein measurements in clinical diagnostics. Prior to joining PPI, Dr. Anderson was Chief Scientist of the Proteomics Division at Large Scale Biology Corporation (Nasdaq: LSBC), whose proteomics division he co-founded in 1985 (as Large Scale Biology) prior to its merger in 1999 with Biosource Technologies. Dr. Anderson's current primary interests are in virus isolation and rapid analysis, precision protein fractionation and in further advancing automated proteomic analysis.

Dr. Anderson obtained his B.A. in Zoology (1947), an M.A. in Physiology (1948), and a Ph.D. in Biochemistry (1951) from Duke University. During his eventful career, Dr. Anderson has served as Director of the Molecular Anatomy Program of the US Department of Energy, first at the Oak Ridge National Laboratory and later at the Argonne National Laboratory. During his time at Oak Ridge, he invented the first high-pressure liquid chromatography systems, the zonal ultracentrifuge (used for the discovery and, later, industrial production of viruses for vaccines, including hepatitis) and the centrifugal fast analyzer (which revolutionized clinical chemistry in the 1970's). At Argonne, he pioneered (with Leigh Anderson) the development of two-dimensional electrophoresis into a high-throughput research tool for proteomics.

Dr. Anderson holds 31 patents and has written over 300 scientific publications in cell physiology, cell fractionation, radiation biology, ultracentrifuge develop­ment, vaccine purification, development of immunological techniques, development of centrifugal fast clinical analyzers, rapid recycling affinity chromatography, the theory of perfect sets, evolutionary significance of viral transmission of host genes, high resolution two-dimensional electrophoresis, electrophoretic protein mapping and database pro­duction and management, large-scale cloning and dot-blot hybridization, multiple-parallel peptide synthesis, large scale synthesis of antisense oligonucleotides, and development of rapid methods for detecting and diagnosing viral infections in man. He has received 17 Small Business Innovation Research (SBIR) grants.

Invited lectures include the Pasteur Institute's 100 Anniversary Commemoration of the Death of Louis Pasteur; the Arne Tiselius Lectureship, Sandefjord, Norway, June 1989. Awards include receipt of the Distinguished Clinical Chemist Award from the International Federation for Clinical Chemistry in San Francisco, July 22, 1990; the Tennessee Technology Foundation Outstanding Scientist Award, 1986; the Career Patent Leader Award, 1984, Argonne National Laboratory; the 1983 Pittsburgh Analytical Chemistry Award for work in high resolution two-dimensional electrophoresis (shared with N. Leigh Anderson); an Docteur Honoris Causa, University of Nancy, France; the John Scott Medal and Award for the invention of the zonal ultracentrifuge, December, 1972 (previous winners include M Curie, Fleming, Land, and Wright); the Atomic Energy Commission Citation and Gold Medal for the invention and development of the K-II vaccine-purification ultracentrifuge and for contributions to the development of a purified influenza vaccine presented by Secretary James Schlessinger, December, 1972; the Preis für Biochemische Analytik, awarded by the Deutsche Gesellschaft für Klinische Chemie for the invention and development of the centrifugal fast analyzer as the most outstanding analytical development in clinical chemistry worldwide during a two-year period, 1972; a U.S. Navy Special Citation, 1946, given by Edward Steichen for outstanding work as a combat photographic officer in the submarine service in the Pacific during WWII.

Bibliography